glp1sideeffects.com

Users on Reddit report a wide spectrum of experiences regarding headaches and migraines while using GLP-1 medications. For some, these medications have led to new or worsened headaches, while for others, they have surprisingly resulted in a reduction or even remission of pre-existing migraine conditions.

Negative Experiences with Headaches/Migraines:

Some users report experiencing headaches as a side effect, particularly when starting the medication or with dose changes. One user on a compound GLP-1 mentioned, "I started on a compound and had a lot of side effects. Nausea, gagging, exhaustion, headaches. "[4] Another user experienced "severe nausea and headaches in the days leading up to my next dosage" in the first month. [3]

For individuals with pre-existing migraine conditions, GLP-1s can sometimes exacerbate the issue. A user with fibromyalgia stated, "the worst is the terrible headache/migraine for the first day or two after the shot. "[5] Another shared, "Unfortunately mine are more frequent while on it"[2] and "any GLP1 I’ve been on has made them worse and more frequent. Mounjaro has been the least bad of all of them but the 24-48 hours after my injection are usually pretty bad. "[11]

A user on Ozempic for 18 months reported getting "a migraine on injection day. "[6]

Someone trying various GLP-1s, including Zepbound, noted that for some people, "the meds actually worsen headaches. "[10]

Another user stated, "I tried a glp-1 and it made my migraines worse. "[12]

Positive Experiences with Headaches/Migraines:

Conversely, some users have found significant relief from chronic migraines. One user with a long history of migraines reported a dramatic improvement: "I woke up the day after my first shot on May 1st 2024 without a headache or migraine... I have had three manageable migraines since I started WeGovy last year. I get headaches probably once or twice a month now. "[1] This user also mentioned, "I’ve met a few other people on r/WeGovyWeightLoss, r/AntidietGLP1, and this sub who have also seen either a complete remission from their chronic migraines or at least a reduction. "[13]

Another user linked headache improvement to better blood sugar control: "I’ve not had any blood sugar headaches since I started the meds in Jan. "[7]

A user with fibromyalgia saw a decrease in migraines after being on a lower dose of Terzepatide for 3. 5 months. [8]

Remedies and Preventions Recommended:

Hydration and Electrolytes: This is the most frequently cited remedy.

One user learned they "needed to load up on electrolytes just like I would during a migraine" to combat headaches at the start of medication. [2]

Another user found that "water with electrolytes near shot day helped me a lot" with headaches experienced early on Mounjaro. [14]

A user with fibromyalgia who experienced headaches recommended to "Keep up on electrolytes. "[9]

Managing Blood Sugar: For headaches linked to blood sugar fluctuations, GLP-1s themselves can be a preventative. One user explained, "If I’d go too long without eating... I’d develop a headache... GLP1 meds improve insulin sensitivity... I’ve not had any blood sugar headaches since I started the meds in Jan. "[7]

Dosage Adjustment: Some users found relief by adjusting their dosage.

A user whose migraines worsened on Mounjaro mentioned, "I’m actually going down a dosage because they’ve been so bad on my current dose. "[11]

Another user with fibromyalgia who experienced terrible headaches/migraines after the shot stated they "no longer take it weekly and I can't get to a high enough dose to lose weight again... But it does help my swollen feet, asthma and knee arthritis even at the lowest dose so I still take it 1-2 times a month.