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Urinary Tract Infections (UTIs)

Users on Reddit report varied experiences regarding Urinary Tract Infections (UTIs) while on GLP-1 medications, with several noting an increase in UTIs or new onset, often linked to dehydration, while a few have had different outcomes. The primary remedy and prevention strategy discussed is maintaining adequate hydration, with some users resorting to stopping the medication.

Experiences with UTIs and Bladder Issues:

  • Several users reported an increase in UTIs. One user asked, "Has anyone had an increase in UTIs while on one of the GLP1s? "[1] In response, a user stated, "Huh… Now that you mention it…… I’ve had three this year and I was wondering why I’ve been getting uti’s……. "[3] Another shared, "Wait this is a thing? I never had UTIs and now I’ve had 3 since starting ozempic! "[11]

  • Some experiences have been severe or recurrent. One user mentioned, "Me!!! Since starting GLP-1s I have had several UTIs and am now fighting to get rid of same bacteria, enterococcus. As soon as I go off antibiotics, it comes back with 4 days. I stopped the Monjouro 4 weeks ago hoping I can get the UTI cleared up. No success yet! "[4] Another reported a bad UTI that "went embedded and I've been on antibiotics for 9 months". [10]

  • A user who started semaglutide two months prior said, "I had symptoms of UTI as of 2 days ago. Yesterday hurt so bad and went to the doctor today. I definitely have a UTI. "[8]

  • In contrast, one user with a history of chronic UTIs found relief: "I actually had chronic UTIs my whole life but they stopped for me since being on semaglutide. "[6] This user later confirmed, "Yes! So far, still haven’t had not one UTI. "[7]

  • Users with Interstitial Cystitis (IC) also reported issues. One user experienced "nonstop flares" and found that "the GLP-1 medication suppressed my thirst an extreme amount. As a result, I’ve been severely dehydrated over the past few weeks, and no amount of water seemed sufficient. After stopping the medication earlier this week, I’ve noticed a significant improvement in my symptoms. "[12] Another Mounjaro user noted, "I’ve also had much worse bladder pain since starting the mounjaro. "[14]


Potential Causes Mentioned by Users:

  • Dehydration: This is the most commonly cited reason for increased UTIs or bladder issues. One user theorized, "i think if there is an increase it will come from dehydration. As the GLP1 reduces appetite, it also reduces thirst. A lot of the side effects of GLP1s are purely dehydration. "[2]

  • A user who developed a UTI was told by their doctor it was because "I haven’t been drinking enough water". [8] Another linked their UTI to increased dosage and decreased water intake, stating, "it’s def because my dosage went up but my water intake went down". [9]

  • The significant dehydration experienced by some is highlighted by a user on a GLP-1 for over a year: "I have SEVERE dehydration... I have a 32 oz water bottle that I fill between 10-12 times a day and probably 2-3 times a night. I also take electrolytes to try to help... In the am, my urine is yellow but by noon it’s crystal clear. "[15]


Remedies and Preventions Recommended:

  • Increased Hydration: The most emphasized prevention and remedy is drinking more water. Users attribute UTIs to not drinking enough water and doctors reportedly advise staying hydrated. [2, 8, 9, 12] One user generally commented on GLP-1s, "It really seems to me that a huge percentage of side effects people experience with these meds could be headed off by simply increasing fluid intake aggressively. "[19]

  • Stopping Medication: Some users felt the need to discontinue their GLP-1 medication due to persistent UTIs or bladder flares. [4, 5, 12] One user stated, "I stopped the Monjouro 4 weeks ago hoping I can get the UTI cleared up. "[4] Another said, "I’m struggling with the same thing I stopped the injection 2 weeks ago because of multiple utis since starting. "[5]

  • Electrolytes: While not a direct UTI remedy, users experiencing severe dehydration mentioned using electrolytes, which could support overall hydration efforts.
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